TABLE 1.
Correlations of RNA levels in the TG and corneas of mice with increased CSa
| RNA transcript | Correlation with CS of increased levels in:
|
|
|---|---|---|
| TG | Cornea | |
| LAT | Yesb | Not detected |
| IL-2 | No | Yesb |
| IL-4 | Yesb | Yesb |
| IFN-γ | No | Yesc |
| CD4 | Yesb | Yesb |
| CD8 | Yesc | Yesb |
| F4/80 | Yesb | Yesb |
| CD11b | Yesb | No |
| CD11c | No | Yesc |
| CD45RO | No | Yesc |
| GzmA | Yesc | Yesc |
| GzmB | Yesc | Yesc |
| PD-1 | Yesc | Not done |
a
Statistical analyses were performed using Spearman's coefficient of rank correlation as described in Materials and Methods. Yes means that there was a statistically significant correlation between increased levels of the RNA transcripts and mice having CS in both eyes (rather than no CS in both eyes). No means no correlation.
b
Correlations were significant at a P value of <0.05.
c
Correlations were significant at a P value of <0.01.