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VV loads in ovaries after surrogate challenge corresponded to prechallenge T-cell responses. Immunized and naïve rats were challenged by vSIVgag-pol as described in Materials and Methods. Ovaries were collected and assayed on BS-C-1 cells to determine VV loads 3 days postchallenge. Naïve rats served as a control. Data represent viral loads in individual rats, and bars indicate the geometric mean for each group.
