TABLE 2.

Protein structures with z values of ≥5 identified by a DALI search of the PDB with SUD-M(527−651)

PDB accession no.a	z scoreb	RMSDc	% Iseqd	Descriptione
2ACF	10.2	2.9	5	ADP-ribose-1"-phosphatase from SARS-CoV (nsp3b)*
2DX6	9.8	2.5	11	Conserved hypothetical protein; TTHA0132 from Thermus thermophilus HB8*
1YD9	9.4	2.9	10	Structural protein; nonhistone domain of the histone variant macroH2A1.1 of human macrodomain*
1SPV	8.8	2.9	11	Putative phosphatase of E. coli*
1GYT	8.7	2.6	11	Aminopeptidase A from E. coli
1VHU	8.6	3.1	7	Putative phosphoesterase; hypothetical protein AF1521 from Archaeoglobus fulgidus*
1ZR5	8.4	3.1	8	Gene regulation; macrodomain of human core histone variant macroH2A1.2, residues 161-372, forms A and B*
2JYC	7.8	2.8	11	Human protein C6orf130; putative macrodomain*
2FG1	7.7	2.7	11	Hypothetical protein BT1257 from Bacteroides thetaiotaomicron
1NLF	5.9	3.6	11	Human interleukin-19; helical cytokine
1OYW	5.2	3.4	8	ATP-dependent DNA helicase; E. coli RecQ catalytic core
1W4R	5.1	3.0	3	Type II thymidine kinase from Homo sapiens
2Q6T	5.0	3.3	8	Hydrolase; Thermus aquaticus DnaB helicase monomer

^aPDB accession numbers from http://www.rcsb.org/pdb.

^bThe z score gives a quantitative measure for structural similarity and is defined in terms of equivalent intramolecular distances (16).

^cRMSD calculated for the C^α atoms of residues in structurally equivalent positions of SUD-M(527−651).

^d% I_seq, Percentage of sequence identity for the aligned residues with SUD-M(527−651).

^eProteins labeled with an asterisk form a macrodomain fold.