FIG. 8.
Coreceptor usage of SIVgor. JC53-BL cells were pretreated with AMD3100 (inhibitor of CXCR4), TAK779 (inhibitor of CCR5), or both prior to addition of the virus preparations indicated. Virus infectivity is plotted on the vertical axis as a percentage of the untreated control. Virus derived from the replication-competent molecular clones NL4.3 (X4-tropic), YU2C (R5-tropic), and WEAU1.6 (dual tropic) as well as the primary isolates 97US08692A (group O) and YBF30 (group N) were included for control.