TABLE 4.
Comparison of circulating immune complexes with WHs antigenemia, WHV viremia, and anti-WHc response in woodchucks with established chronic WHV infection
| Woodchucka | CIC (signal strength)b | WHsAg (ODU) | WHV DNA (WHVge/ml) | Anti-WHc (ODU) |
|---|---|---|---|---|
| M6539 | +++ | 0.319 | 7.5 × 1010 | 0.295 |
| F5954 | ++ | 0.228 | 6.7 × 1010 | 0.122 |
| M6510 | ++ | 0.177 | 2.6 × 1010 | 0.195 |
| F5904 | + | 0.218 | 7.7 × 109 | 0.226 |
| F5927 | + | 0.183 | 9.2 × 109 | 0.152 |
| M5951 | − | 0.205 | 4.0 × 1010 | 0.122 |
| F5883 | − | 0.196 | 1.8 × 1010 | 0.077 |
| F5890 | − | 0.172 | 7.6 × 109 | 0.097 |
| F5929 | − | 0.154 | 7.2 × 109 | 0.131 |
a
Woodchucks were infected experimentally as neonates at 3 days of age with 5 × 106 WID50 of the WHV7P1 inoculum.
b
+++, high; ++, intermediate; +, low; −, no signal.