TABLE 2.

Effects of telomere size (at the time of senescence) on telomeric recombination on solid medium in telomerase-negative (tlc1Δ) mutants^a

Survivor fate and type of telomeric recombination initiated in the presence of wild-type-length telomeresb	Relevant genotype	Survivor fate and type of telomeric recombination initiated in the presence of overelongated telomeresc
I or II	tlc1Δ	II then Id
I	tlc1Δ rad50Δ	I
II	tlc1Δ rad51Δ	II
Death	tlc1Δ rad52Δ	II
I	tlc1Δ rad59Δ	I
I	tlc1Δ rfa1-t11	II
Death	tlc1Δ rad50Δ rad51Δ	II
I	tlc1Δ rad50Δ rad59Δ	I
NDe	tlc1Δ rad50Δ rfa1-t11	Death (6)
Atypical I	tlc1Δ rad51Δ rfa1-t11	II
Death	tlc1Δ rad59Δ rfa1-t11	Death (2)
Death	tlc1Δ rad50Δ rad51Δ rad59Δ	Death (8)
Death	tlc1Δ rad50Δ rad51Δ rfa1-t11	Death (15)
Death	tlc1Δ rad50Δ rad59Δ rfa1-t11	Death (2)

^aA RAD52⁺ background was used throughout except for the tlc1Δ rad52Δ strain (row 4). Restreak assays were performed.

^bData are from previous work from our laboratory (25, 26).

^cNumbers in parentheses indicate the number of passages before death occurred (∼30 generations per passage).

^dSee Fig. 9.

^eND, not determined.