Fig. 2.

⁸⁶Rb⁺ influx as a function of ion concentration for 3 isoforms of the NKCC2 cotransporter reported in Plata et al. (13). A: Na⁺ concentration was varied from 0 to 97 mM and Cl⁻ and K⁺ concentrations were kept fixed to 110 and 10 mM, respectively. B: Cl⁻ concentration was varied from 0 to 110 mM and Na⁺ and K⁺ concentrations were kept fixed to 97 and 10 mM, respectively. C: K⁺ concentration was varied from 0 to 10 mM and Na⁺ and Cl⁻ concentrations were kept fixed to 97 and 110 mM, respectively. For the A isoform, the continuous line and circles represent model and experimental data, respectively; for the B isoform, the dashed line and squares represent model and experimental data, respectively; and for the F isoform, the dotted line and triangles represent model and experimental data, respectively.