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. 2008 Nov 26;296(2):F369–F381. doi: 10.1152/ajprenal.00096.2008

Table 6.

Comparison of parameter values from transformation of two cell types published in Benjamin and Johnson (2) to isoforms of the NKCC2 model

Parameter B&J MDCK B&J LLC-PK1 MDCK to A Isoform LLC-PK1 to A Isoform MDCK to B Isoform LLC-PK1 to B Isoform MDCK to F Isoform LLC-PK1 to F Isoform
KNa, l/mol 2.18 44.69 17.50 31.95 1.958 5.037 29.75 39.56
KCl, l/mol 50.72 413.29 22.71 22.52 999.8 768.3 3.864 5.473
KK, l/mol 88.43 4.26 397.9 399.4 3.779 5.28 901.4 617.0
kff, s−1 1,791 1,406 893.6 900.3 1791 1,406 1,791 1,406
kbf, s−1 9,765 4,025 9,765 4,025 9,765 4,025 9,765 4,025
kfe, s−1 37,767 37,767 37,767 37,767 37,767 37,767 37,767 37,767
kbe, s−1 6,927 13,193 3,456 8,448 6,927 13,193 6,927 13,193

Parameter values for transformation of MDCK and LLC-PK1 cells from Benjamin and Johnson (2) to the A, B, and F isoforms of the NKCC2 models. For comparison, the parameter values reported in Tables 3 and 4 by Benjamin and Johnson (2) for the LLC-PK1 and MDCK cells are included (B&J).