Fig. 3.
Metal concentrations in the liver, blood, and serum. A portion of the large lob of the liver, whole blood, and serum were collected from 2-mo (female) and 10-mo-old (male) Ctr1F/F and Ctr1F/FAlb-Cre mice. Samples were digested in nitric acid, and then copper (Cu) (A), iron (Fe) (B), and zinc (Zn) (C) concentrations were measured by inductively coupled plasma mass spectrometry (ICP-MS). Each bar represents the mean ± SD of data obtained from at least 6 mice. *P < 0.005; **P < 0.001, Student's t-test.