Fig. 3.

Body weight and bone mineral content. WT, IL-10 KO, APN KO, and double IL-10 APN KO males (A) and females (B) were weighed weekly starting at age 4 wk. Both male and female IL-10 KO and double IL-10 APN KO mice were significantly smaller than WT and APN KO mice, respectively, at all time points after age 6 wk. C and D: whole-body BMC was evaluated by dual-energy X-ray absorptiometry (DEXA) in males (C) and females (D). Data are means ± SE. N = 18–22 for A and B and N = 7–10 for C and D. ***P < 0.001 WT vs. IL-10 KO mice and APN KO vs. IL-10 APN KO mice.