Table 2.
Pfam families with the highest and lowest SNP A/S ratios
| Pfam accession | A/S ratio | Number of proteins | Pfam description |
|---|---|---|---|
| PF05296 | 0.49 | 55 | Mammalian taste receptor protein (TAS2R) |
| PF00001 | 0.49 | 558 | 7 transmembrane receptor (rhodopsin family) |
| PF02798 | 0.47 | 20 | Glutathione S-transferase, amino-terminal domain |
| PF00043 | 0.46 | 24 | Glutathione S-transferase, carboxy-terminal domain |
| PF01454 | 0.45 | 24 | MAGE family |
| PF09723 | 0.44 | 42 | Putative regulatory protein (CxxC_CxxC_SSSS) |
| PF02023 | 0.44 | 39 | SCAN domain |
| PF00059 | 0.43 | 58 | Lectin C-type domain |
| PF07859 | 0.42 | 21 | alpha/beta Hydrolase fold |
| PF00048 | 0.40 | 23 | Small cytokines (intecrine/chemokine), interleukin-8 like |
| PF00105 | 0.14 | 38 | Zinc finger, C4 type (two domains) |
| PF00536 | 0.14 | 68 | SAM domain (Sterile alpha motif) |
| PF07649 | 0.13 | 45 | C1-like domain |
| PF00125 | 0.13 | 25 | Core histone H2A/H2B/H3/H4 |
| PF00535 | 0.13 | 27 | Glycosyl transferase family 2 |
| PF01437 | 0.13 | 31 | Plexin repeat |
| PF00335 | 0.13 | 23 | Tetraspanin family |
| PF00350 | 0.12 | 28 | Dynamin family |
| PF07707 | 0.11 | 36 | BTB And C-terminal Kelch |
| PF00433 | 0.09 | 33 | Protein kinase C terminal domain |
Top part: ten families with the highest A/S ratios. Bottom part: ten families with the lowest A/S ratios.