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. 2008 Dec 17;296(2):R454–R466. doi: 10.1152/ajpregu.90460.2008

Fig. 11.

Fig. 11.

A: TRPV4 and flotillin distributions over sucrose density gradients in the hypothalamus of BDL rats and BDL rats given 2% saline to drink (BDL+sal). The fraction number 4 corresponds to the lipid raft fraction. TRPV4 immunoreactivity was quantified by densitometry using the Scion program, and the respective values were normalized by the flotillin densitometry in four independent experiments. Values are expressed as means ± SE, ***Statistically significant different from sham, P < 0.001. **Statistically significant different from sham, P < 0.01. aStatistically significant difference from BDL, P < 0.001. B: linear regression analysis of AVP and TRPV4 immunoreactivity in lipid raft (fraction #4) from total hypothalamus in all three groups. C: linear regression analysis of PRA and TRPV4 immunoreactivity in lipid raft (fraction number 4) of total hypothalamus from sham, BDL, and BDL+ saline.