Fig. 7.

Effect of adoptive transfer of wild-type and AT₂R^−/− T cells on the hypertensive response to ANG II. Ten million T cells were adoptively transferred from spleens of either C57BL/6 (n = 7) or AT₂R^−/− mice (n = 11) into RAG1^−/− mice by tail vein injection. Three weeks later, either sham or ANG II infusion was initiated. A: blood pressure response over 14 days of ANG II infusion. Also shown is the hypertensive response to ANG II in C57BL/6 mice (n = 6). B: example flow cytometry plots confirming reconstitution of T cells, but not B cells.