Table 2.
Baseline characteristics of SCD-HeFT patients, stratified by imaging modality
| Baseline | Nuclear | Contrast | Echo |
|---|---|---|---|
| Characteristic | (N = 616) | (N = 436) | (N = 1469) |
| Randomized treatment | |||
| ICD | 34% (207) | 31% (137) | 33% (485) |
| Amiodarone | 33% (201) | 33% (146) | 34% (498) |
| Placebo | 34% (208) | 35% (153) | 33% (486) |
| Age (years) | 60 (53, 68) | 59 (52, 68) | 60 (51, 69) |
| Female | 21% (131) | 25% (111) | 24% (346) |
| Nonwhite race | 17% (104)* | 27% (118) | 25% (367)+ |
| Weight (lbs) | 190 (166, 221) | 193 (167, 222)! | 187 (162, 218)+ |
| NYHA Class | |||
| II | 71% (438) | 70% (304) | 69% (1019) |
| III | 29% (178) | 30% (132) | 31% (450) |
| HF etiology | |||
| Ischemic | 63% (391)* | 45% (198) | 49% (721)+ |
| Non-ischemic | 37% (225) | 55% (238) | 51% (748) |
| Ejection fraction | 26 (20, 31)* | 20 (15, 28)! | 25 (20, 30)+ |
| Prior CABG | 33.0% (203)* | 19.5% (85)! | 26.1% (384)+ |
| Prior PCI | 17.8% (171)* | 19.5% (85)! | 17.7% (260)+ |
| Any prior revascularization | 46.9% (289)* | 30.7% (134)! | 35.5% (521)+ |
| Diabetes | 35% (215) | 31% (134) | 28% (418)+ |
| Pulmonary disease | 15% (95)* | 22% (95) | 20% (290)+ |
| Hyperlipidemia | 60% (372)* | 47% (206) | 51% (751)+ |
| Hypertension | 53% (324) | 58% (253) | 56% (823) |
| Atrial Fib/Flutter | 13% (80) | 14% (60) | 17% (250)+ |
| Nonsustained VT | 18% (112)* | 25% (110) | 25% (361)+ |
| Syncope | 7% (42) | 4% (19)! | 7% (101) |
| EP study | 11% (67)* | 21% (91) | 17% (249)+ |
| QRSd>=120 ms | 44% (271)* | 36% (155)! | 41% (607) |
| Systolic BP | 117 (104, 130)* | 120 (108, 136)! | 118 (106, 130) |
| Diastolic BP | 70 (60, 78)* | 70 (62, 80) | 70 (62, 80)+ |
| Heart rate (bpm) | 72 (63, 80)* | 76 (65, 84) | 74 (64, 84)+ |
| Beta blocker | 72% (445) | 67% (293) | 68% (1,000) |
| ACE-Inhibitor | 82% (506) | 86% (373) | 85% (1,254) |
| Aspirin or warfarin | 85% (525)! | 77% (334)+ | 82% (1,199)* |
BP=Blood Pressure; BPM=Beats per Minute; CABG=Coronary artery bypass graft; Contrast=Contrast angiography; Echo=Echocardiography; HF=Heart Failure; ICD=Implanted Cardioverter-defbrillator; Nuclear=Nuclear angiography; NYHA=New York Heart Association; PCI=Percutaneous coronary intervention; QTSd=QRS duration; VT=Ventricular Tachycardia
*
Nuclear different from contrast angiography at p<0.05.
!
Contrast angiography different from Echo at p<0.05.
+
Echo different from Nuclear at p<0.05.