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. Author manuscript; available in PMC: 2009 Feb 17.
Published in final edited form as: Xenobiotica. 2008 Jul;38(7-8):889–935. doi: 10.1080/00498250801927435

Table IV.

Substrate specificity (apparent Km) of OAT2 among three different species (μM).

PGE2 Salicylate Glutarate α-KG
rOat2 38.5b, Ta 81.2b, 88a n.d. 17.8a
mOat2 0.005c Not transportedc 15.8c Tc
hOAT2 0.71e, Td Td Td Td

Notes:

a

Oocyte-expressing rOat2 (Sekine et al. (1998).

b

LLC-PK-expressing rOat2 (Morita et al. (2001).

c

Oocyte-expressing mOat2 (Kobayashi et al. (2002).

d

Oocyte-expressing hOAT2 (Kobayashi et al. (2005b).

e

S2 cells-expressing hOAT2, S2hOAT2 (Kumura et al. (2002).

n.d., Not determined; T, transported.