Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Enzastaurin-induced accumulation of β-catenin triggers UPR-mediated growth arrest and c-Jun-mediated apoptosis. Enzastaurin inhibits phosphorylation of β-catenin, thereby inducing accumulation of β-catenin leading to ER stress response-mediated growth arrest, as well as triggering apoptosis via c-Jun-stabilized p73.
