Fig. 3.

Active site of LpxR. (A) Surface representation of LpxR in wheat color. Positions of fully conserved residues are shown in dark green. Residues that are largely conserved are shown in light green. (B) Close up of the active site of LpxR. The orientation of LpxR is identical to that in Fig. 2A. Zn²⁺ ions are shown as gray spheres, a water molecule as a red sphere, and a glycerol molecule is represented as sticks with green carbons. Oxygen atoms are colored red and nitrogen blue. Short distances, i.e., H bonds or shorter distances between noncovalently bonded atoms, are shown as blue dashed lines.