TABLE 1.
MEMBRANE-ASSOCIATED MUCINS
| Human Gene | Locus | Mouse Gene | Locus | Tissue Distribution |
|---|---|---|---|---|
| MUC 1 Aliases: episialin, DF3 antigen, H23 antigen, epithelial membrane antigen, polymorphic epithelial mucin, peanut-reactive urinary mucin | 1q21 | Muc1 Aliases: epithelial membrane antigen, CD227 | 3F 1 | Cornea, salivary glands, esophagus, stomach, pancreas, large intestine, lung, breast, prostate, ovary, kidney, uterus, cervix, dendritic cells |
| MUC3A Alias: Muc3 | 7q22 | Muc3 | 5 G2 | Thymus, small intestine, colon, kidney |
| MUC3B | 7q22 | Small intestine, colon | ||
| MUC4 Aliases: HSA276359 | 3q29 | Muc4 | 16 B2 | Cornea, lung, salivary glands, esophagus, small intestine, kidney, endocervix |
| MUC11 | 7q22 | Middle ear, thymus, lung, small intestine, Pancreas, Colon, liver, kidney, uterus, prostate | ||
| MUC12 | 7q22 | Middle ear, pancreas, colon, uterus, prostate | ||
| MUC13 Aliases: downregulated in colon cancer 1 | 3q13 | Muc13 Aliases: Lrrp, NJ-1, 14/A10, lymphocyte antigen 64 | 16B3 | Conjunctiva, stomach, small intestine, colon, lung, kidney |
| MUC14 Aliases: endomucin | 4q24 | Muc14 Aliases: endomucin | 3 G3 | Endothelium |
| MUC15 Aliases: PAS III, PAS3, GLYCOPROTEIN C, GLYCOPROTEIN 4, COMPONENT II | 11p14 | Muc15 | 2 E 3 | Conjunctiva, tonsils, thymus, lymph node, breast, small intestine, colon, liver, spleen, prostate, testis, ovary, leukocytes, bone marrow |
| MUC16 Alias: CA125 ovarian cancer antigen | 19q13.2 | Muc16 | 9 A2 | Conjunctiva, ovary |
| MUC17 | 7q22 | Intestinal cells, conjunctival epithelium | ||
| MUC18 Aliases: melanoma cell adhesion molecule (MCAM), CD146 | 11q23.3 | Muc18 Aliases: l-gicerin protein, CD146, CD149, s-endo, s-gicerin | 9 A5.2 | Prostate |
| MUC20 | 3q29 | Muc20 | 16 B2 | Lung, liver, kidney, colon, placenta, prostate |