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. 2006 Jan 13;34(5):552–560. doi: 10.1165/rcmb.2005-0378OC

Figure 1.

Figure 1.

Kinetics of doxycycline-induced uPA expression. TetO-muPA:CCSP-rtTA mice were maintained on regular drinking water until 6–8 wk of age and then switched to doxycycline treatment (time 0). After the indicated time intervals, BAL fluid was collected and uPA activity was assessed using casein zymography, as shown in A. In B, tetO-muPA:CCSP-rtTA mice were maintained on regular drinking water until 6–8 wk of age and then switched to doxycycline treatment for 7 d. Thereafter the mice were returned to regular drinking water and BAL fluid was collected for casein zymography from two animals after the indicated time intervals.