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The effect of CCSP:rtTA on lung compliance and TLC in the absence of doxycycline treatment. CCSP-rtTA–positive and CCSP-rtTA–negative mice were maintained on regular water throughout the course of the study. At the indicated times, the animals underwent measurement of TLC and compliance using a whole body plethysmograph. The data are presented as means ± SEM (n = 3–14 mice/genotype/time point).
