Figure 3.

Candidate genes based on the physiologic and biologic response to ovalbumin (OVA). This figure illustrates differential expression of candidate genes in the mouse lung after OVA challenge along with proposed associations with phenotypes in the OVA asthma model. Differentially expressed genes were selected based on a significant change of ± 1.5-fold due to OVA treatment in the time course and, where identified, as responses leading to the promotion or protection of airway hyperresponsiveness (AHR) (129/SvIm and BALB/cJ) or eosinophil (EOS) (129/SvIm and C57BL/6J) phenotypes. Data shown as the Log₂ (OVA/alum) from two to four measurements.