Table 1.
Summary of the average baseline hemodynamic values of the dogs and the average effect of each of the employed interventions on these values
| Condition | CO | LAP | Mean PAP | Mean ABP | RVSP | RVDP | HR |
|---|---|---|---|---|---|---|---|
| Baseline | 2.76±0.85 | 7.1±1.4 | 13.7±2.7 | 88.3±10.8 | 25.1±6.4 | 2.6±1.8 | 134±8 |
| Dobutamine | 40.1±17.9 | 14.0±23.0 | 42.4±19.6 | 27.7 | 46.9±14.9 | 51.3±116.7 | 8.1±4.3 |
| Isoproterenol | 103.4 | −20.7 | 46.2 | −23.2 | N/A | N/A | 18.3 |
| Esmolol | −0.1±20.5 | 52.1±40.3 | 24.8±9.5 | −1.3±25.4 | 9.0±21.6 | 470.2±259.0 | −7.4±3.6 |
| Phenylephrine | −9.8±12.5 | 98.0±60.0 | 61.8±40.4 | 64.7±12.2 | 31.1±27.7 | 113.4±118.7 | −4.0±4.1 |
| Nitroglycerin | 5.7±14.1 | 37.6±49.1 | 21.2±29.2 | −15.8 | 4.9±10.9 | 87.9±148.1 | −0.1±1.2 |
| Volume | 40.4 | 57.4 | 26.1 | −24.3 | 29.4 | 585.8 | −3.2 |
| Hemorrhage | −7.3 | −17.6 | 18.9 | N/A | N/A | N/A | 7.4 |
Values are given as means ± SE over the dogs (unless only one dog was available). Baseline values are expressed in physical units of l/min for CO, mmHg for pressures, and beats/min for HR, whereas intervention values are presented as percent changes relative to the baseline values. CO, cardiac output; LAP, left atrial pressure; PAP, pulmonary artery pressure; ABP, arterial blood pressure; RVSP, right ventricular systolic pressure; RVDP, right ventricular diastolic pressure; HR, heart rate.