TABLE 2.

Serum TNF-α Concentration in SLD/LPS-Treated Rats

Treatment	Veh	SLD
Veh	0.024 ± 0.005	0.057 ± 0.018
LPS	16.9 ± 6.5*	50.2 ± 10.7*#

Note. Rats were treated with SLD (50 mg/kg, p.o.) or its vehicle (0.5% methyl cellulose) at −16 h, and food was removed. At −0.5 h rats received LPS (8.25 × 10⁵ EU/kg, i.v.) or its vehicle (saline), and 30 min later they were given a second administration (50 mg/kg) of SLD. Serum samples were collected at 1 h after the second administration of SLD. The concentration of TNF-α (ng/ml) in serum was determined using ELISA. *Significantly different from corresponding group not treated with LPS. #Significantly different from Veh/LPS group. p < 0.05, n = 3–7.