Skip to main content
. Author manuscript; available in PMC: 2009 Aug 15.
Published in final edited form as: Cancer. 2008 Aug 15;113(4):733–742. doi: 10.1002/cncr.23601

TABLE 1.

Ovarian Cancer Risk in Hereditary Nonpolyposis Colorectal Cancer

Reference Ascertainment Source Location Sample Size Relative Risk Cumulative Incidence, %
Watson & Lynch 199343 1300 High-risk members from 23 HNPCC kindreds Nebraska 13 3.5 -
Aarnio 199542 293 Putative HNPCC gene carriers from 40 families Finland 14 - 9
Vasen 199641 382 Relatives from 19 families with HNPCC mutations Netherlands 2 8 -
Aarnio 199945 1763 High-risk members from 50 HNPCC families Finland 13 13 12
Brown 200144 120 HNPCC families Australia 24 5 (by age 40 y) -

HNPCC indicates hereditary nonpolyposis colorectal cancer.