Table 1.

Risk Factors for QTc Prolongation

Risk Factor
Older age
Female gender
Structural heart disease
HIV infection
Low potassium level
Low prothrombin level
Higher methadone dose
Cytochrome P450 3A4 inhibitor use
Alcohol use
Cocaine use
Prolonged baseline QTc
Family history of prolonged QTc
History of drug-induced torsades de pointes
Antidepressant use
Antipsychotic use
Antiretroviral use
Antibiotic use
Potassium-lowering agent use
Magnesium-lowering agent use