Table 5.
mRNA Expression of Enzymes in Muscle Tissue Following Dietary Interventions (Means±SE)
| High Fat | High Sucrose | |||
|---|---|---|---|---|
| LD | HD | LD | HD | |
| CPT-1βa | 1.00+0.23 | 1.45+0.32 | 1.00+0.14 | 0.99+0.17 |
| PGC-1αb | 1.00+0.13 | 2.32+0.24* | 1.00+0.23 | 0.71+0.06 |
| UCP2 d | 1.00+0.24 | 0.65+0.04 | 1.00+0.13 | 1.07+0.18 |
| UCP3 | 1.00+0.14 | 0.78+0.18 | 1.00+0.30 | 0.92+0.18 |
| VEGF e | 1.00+0.19 | 0.86+0.19 | 1.00+0.25 | 1.28+0.24 |
| Myostatin | 1.00+0.20 | 1.14+0.30 | 1.00+0.34 | 0.95+0.29 |
| Insulin Receptor | 1.00+.18 | 2.20+0.45* | 1.00+0.40 | 1.94+0.39* |
a
Data is expressed over LD average for background diet. Statistical analyses compared LD and HD within dietary background (high fat or high sucrose) by two tailed T test.
Asterisk (*) indicates significant difference between HD and LD groups within dietary background.
Abbreviations are carnitine palmitoyltransferase-1β (CPT-1β), Peroxisome proliferative activated receptor γ coactivator-1α (CPT-1α), Uncoupling Protein (UCP) and Vascular Endothelial Growth Factor (VEGF).