Table 3.
Acid–base status, fluid balance and serum electrolytes
| Dialysate ionized calcium concentration (mmol/l) | t-test | |||
|---|---|---|---|---|
| 1.25 | 1.5 | |||
| BNP (ng/l) | Pre-dialysis | 863 ± 719 | 858 ± 810 | Ns |
| ECW (l) | Pre-dialysis | 21.4 ± 4.5 | 20.8 ± 4.1 | Ns |
| ICW (l) | Pre-dialysis | 16.9 ± 4.8 | 17.0 ± 4.8 | Ns |
| Weight loss during dialysis (kg) | 1.23 ± 0.64 | 1.28 ± 0.70 | Ns | |
| Ultrafiltered volume (l) | 1.34 ± 0.65 | 1.43 ± 0.68 | Ns | |
| Free water deficit (ml) | Post-dialysis | −174 ± 447 | 0 ± 450 | <0.05 |
| Dialyses with need of staff intervention (%) | 12 ± 17 | 10 ± 13 | Ns | |
| Sodium, whole blood (mmol/l) | Pre-dialysis | 134.1 ± 2.1 | 134.6 ± 2.5 | Ns |
| Post-dialysis | 133.3 ± 1.4 | 134.6 ± 1.5 | <0.001 | |
| Potassium, whole blood (mmol/l) | Pre-dialysis | 5.49 ± 1.58 | 4.92 ± 0.55 | Ns |
| Post-dialysis | 3.86 ± 0.30 | 3.88 ± 0.26 | ns | |
| pH, whole blood | Pre-dialysis | 7.39 ± 0.03 | 7.38 ± 0.03 | ns |
| Post-dialysis | 7.48 ± 0.04 | 7.45 ± 0.04 | <0.01 | |
| Calcium, ionized, whole blood (mmol/l) | Pre-dialysis | 1.13 ± 0.12 | 1.10 ± 0.08 | Ns |
| Post-dialysis | 1.11 ± 0.08 | 1.19 ± 0.05 | <0.001 | |
| Dialysate bicarbonate concentration (mmol/l) | ||||
| Low (range 26–29) | High (range 32–35) | |||
| BNP, pre-dialysis (ng/l) | Pre-dialysis | 924 ± 905 | 754 ± 703 | 0.05 |
| ECW (l) | Pre-dialysis | 20.9 ± 4.0 | 21.5 ± 4.3 | 0.05 |
| ICW (l) | Pre-dialysis | 17.0 ± 4.8 | 16.8 ± 4.7 | ns |
| Weight loss during dialysis (kg) | 1.40 ± 0.83 | 1.36 ± 0.79 | ns | |
| Ultrafiltered volume (l) | 1.67 ± 1.07 | 1.65 ± 1.12 | ns | |
| Free water deficit (ml) | Post-dialysis | −13 ± 557 | −42 ± 524 | ns |
| Sodium removal (mmol) | 184.6 ± 106.8 | 197.7 ± 109.5 | ns | |
| Dialyses with need of staff intervention (%) | 9 ± 12 | 10 ± 20 | ns | |
| Sodium, whole blood (mmol/l) | Pre-dialysis | 134.5 ± 2.4 | 134.5 ± 2.7 | ns |
| Post-dialysis | 134.6 ± 1.6 | 134.1 ± 1.6 | <0.05 | |
| Potassium, whole blood (mmol/l) | Pre-dialysis | 5.00 ± 0.54 | 5.22 ± 1.63 | ns |
| Post-dialysis | 3.91 ± 0.23 | 3.74 ± 0.24 | <0.001 | |
| pH, whole blood | Pre-dialysis | 7.36 ± 0.05 | 7.41 ± 0.09 | 0.05 |
| Post-dialysis | 7.44 ± 0.06 | 7.51 ± 0.04 | <0.001 | |
| Calcium, ionized, whole blood (mmol/l) | Pre-dialysis | 1.14 ± 0.09 | 1.12 ± 0.11 | ns |
| Post-dialysis | 1.19 ± 0.08 | 1.14 ± 0.06 | <0.01 | |
Pre-dialysis BNP, extra- and intra-cellular body water (ECW and ICW, respectively), free water deficit at the end of dialysis,% of dialyses with need of staff intervention, pH in whole blood and serum ionized calcium, potassium and sodium at the beginning and at the end of the dialysis sessions using low or high dialysate calcium and bicarbonate concentrations.
Significant differences are highlighted in bold; ns: non significant.