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Dose levels at end of SR phase
| OROS® hydromorphone (N = 77) | CR morphine (N = 86) | |||
| Dose level | Dose (mg) every 24 hours | Number of subjects (%) | Dose (mg) every 12 hours | Number of subjects (%) |
| 1 | 16 | 22 (28.6) | 30 | 25 (29.1) |
| 2 | 24 | 14 (18.2) | 60 | 23 (26.7) |
| 3 | 32 | 18 (23.4) | 90 | 15 (17.4) |
| 4 | 48 | 10 (13.0) | 120 | 13 (15.1) |
| 5 | 72 | 5 (6.5) | 175 | 8 (9.3) |
| 6 | 96 | 8 (10.4) | 260 | 2 (2.3) |
Abbreviations: CR, controlled-release; SR, sustained-release
