Table 2.
Body weight, heart weight, and hemodynamic data after exposure to 10% O2 (hypoxia) or room air
(normoxia)
Normoxia | Hypoxia | |||
IL-6+/+ n = 8 | IL-6-/- n = 8 | IL-6+/+ n = 8 | IL-6-/- n = 8 | |
Final body weight (g) | 25.2 ± 0.3 | 22.9 ± 0.5** | 24.7 ± 0.6 | 20.6 ± 0.7** |
RV/BW (mg/g) | 0.96 ± 0.02 | 0.85 ± 0.03 | 1.24 ± 0.07$$$ | 1.02 ± 0.07* |
LV/BW (mg/g) | 3.8 ± 0.06 | 3.7 ± 0.15 | 3.6 ± 0.1 | 3.9 ± 0.1 |
Heart rate (beats/min) | 308 ± 21 | 318 ± 24 | 327 ± 11 | 318 ± 23 |
All values are mean ± SEM.
*P < 0.05 and **P < 0.01 compared with corresponding values in wild type mice.
$P < 0.05 and $$P < 0.01 compared with corresponding values under normoxia.
RV/BW, right ventricular weight/body weight; LV/BW, left ventricular weight/body weight.