Table 3.
HSP-90 expression and intensity of staining and clinicopathological characteristics of the 66 patients with gastric adenocarcinoma
| Clinicopathological Characteristics | HSP-90 expression | HSP-90 intensity | |||||
|---|---|---|---|---|---|---|---|
| n = 66 | < 48%(%) | ≥ 48% (%) | p-value | +(%) | ++(%) | +++(%) | p-value |
| All cases | 33(50) | 33(50) | 30(45) | 31(47) | 5(8) | ||
| Age | 0.196 | 0.629 | |||||
| < 67 | 14(21) | 9(14) | 12(18) | 10(15) | 1(2) | ||
| ≥ 67 | 19(29) | 24(36) | 18(27) | 21(32) | 4(6) | ||
| Gender | 0.786 | 0.276 | |||||
| Male | 23(35) | 24(36) | 22(33) | 23(35) | 2(3) | ||
| Female | 10(15) | 9(14) | 8(12) | 8(12) | 3(5) | ||
| Histological type | 0.621 | 0.070 | |||||
| Intestinal | 14(21) | 16(24) | 13(20) | 17(25) | 0(0) | ||
| Diffuse | 19(29) | 17(26) | 17(25) | 14(22) | 5(8) | ||
| Histological grade | 0.834 | 0.661 | |||||
| Well differentiated | 2(3) | 1(2) | 2(3) | 1(2) | 0(0) | ||
| Moderately differentiated | 15(22) | 15(24) | 14(21) | 15(22) | 1(2) | ||
| Poorly differentiated | 17(25) | 15(24) | 14(21) | 15(23) | 4(6) | ||
| pT classification | 0.240 | 0.020 | |||||
| T1 | 7(11) | 2(3) | 8(12) | 1(2) | 0(0) | ||
| T2 | 9(14) | 13(20) | 7(10) | 14(22) | 1(2) | ||
| T3 | 15(22) | 14(21) | 13(20) | 14(21) | 1(2) | ||
| T4 | 2(3) | 4(6) | 2(3) | 2(3) | 2(4) | ||
| pN classification | 0.873 | 0.985 | |||||
| N0 | 13(20) | 11(17) | 11(17) | 11(17) | 2(3) | ||
| N1 | 18(27) | 20(30) | 17(25) | 18(27) | 3(5) | ||
| N2 | 2(3) | 2(3) | 2(3) | 2(3) | 0(0) | ||
| pM classification | 0.689 | 0.530 | |||||
| M0 | 29(44) | 30(46) | 26(40) | 29(44) | 4(6) | ||
| M1 | 4(6) | 3(4) | 4(5) | 2(3) | 1(2) | ||
| pStage | 0.250 | 0.114 | |||||
| I | 12(18) | 8(12) | 10(15) | 10(15) | 0(0) | ||
| II | 5(8) | 12(18) | 7(10) | 7(11) | 3(5) | ||
| III | 12(18) | 9(14) | 9(14) | 12(18) | 0(0) | ||
| IV | 4(6) | 4(6) | 4(6) | 2(3) | 2(3) | ||
| Ki-67 protein statement | 1.000 | 0.260 | |||||
| < 75 | 24(36) | 24(36) | 23(35) | 20(30) | 5(8) | ||
| ≥ 75 | 9(14) | 9(14) | 7(10) | 11(17) | 0(0) | ||