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. Author manuscript; available in PMC: 2009 Feb 18.
Published in final edited form as: J Comb Chem. 2006;8(4):513–521. doi: 10.1021/cc060010h

Table 1.

Influence of various Co-Solvents on the catalytic activity of BoNT/A LCa

Methanol(25%) Ethanol (25%) Glycerol (25%) DMSO (25%)
Vcosol./Vo 0.83 ± 0.1 0.41 ± 0.06 1.6 ± 0.6 1.2 ± 0.2
a

Assays were conducted at 22.5 °C, pH 7.4 in 40 mM HEPES 0.01% (W/V) Tween® 20, 5 μM SNAPtide substrate and 200 nM enzyme. Values are the mean ± SEM of triplicate measurements.