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A) parasitemia curves and B) mortality in Swiss mice infected with 5,000 parasites/0.1 mL blood (Y strain P1 trypomastigotes). Parasites were pre-treated with ARL67156, Gadolinium or Suramin as indicated; a negative control assay is included, omitting the parasites' drug pre-treatment. Data are from one experiment using the mean value of a group of 10 mice in each treatment.
