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. 2008 Nov 11;296(2):E272–E281. doi: 10.1152/ajpendo.90473.2008

Fig. 4.

Fig. 4.

A: AUC for endogenous hepatic glucose production during GTT is shown in all Ex and Sed groups. Two-way ANOVA revealed a significant effect of pre/postnatal nutrition alone (F = 3.338, P = 0.03) and exercise × pre/postnatal nutrition (F = 4.64, P < 0.008) but no effect of exercise alone (F = 1.053, P = 0.311). Holm-Sidak test demonstrated differences between the Ex and Sed counterparts at *P < 0.02, **P < 0.04, and ***P < 0.05. B: total glucose clearance (mg·kg−1·min−1) is shown for all Ex and Sed groups. Two-way ANOVA did not demonstrate an effect of exercise (F =1.497, P = 0.229), pre/postnatal nutrition (F = 0.480, P = 0.698), or exercise × pre/postnatal nutrition (F = 2.298, P = 0.094). C: hepatic glucose recycling or glucose futile cycling is shown for all Ex and Sed groups. Two-way ANOVA revealed a significant effect of exercise × pre/postnatal nutrition (F = 3.714, P = 0.02) but no effect of exercise (F = 0.695, P = 0.410) or pre/postnatal nutrition alone (F = 0.581, P = 0.631). Holm-Sidak test demonstrated a difference between the Ex IUGR + PNGR vs. the corresponding Sed group at #P < 0.015; n = 6 for all study groups, except n = 5 each for Sed and Ex PNGR groups alone.