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. 2008 Dec 29;27(5):733–739. doi: 10.1200/JCO.2008.18.9035

Table 2.

Pretreatment Characteristics

Characteristic Interval From Surgery to Start of Radiation
≤ 2 Weeks (n = 756)
> 2 to 3 Weeks(n = 805)
> 3 to 4 Weeks (n = 757)
> 4 Weeks (n = 537)
No. % No. % No. % No. %
Days from surgery to start of radiation
    Median 12 19 26 33
    Range 1-14 15-21 22-28 29-73
Age, years
    Median 57 56 57 55
    Range 14-83 19-83 18-86 17-82
Dose, Gy
    No. of patients with dose 494 676 672 424
    Median 60 60 60 60
    Range 1.7-82.87 6-85.68 2-86 2-84.32
Performance score*
    Karnofsky
        20-50 77 11 36 4 21 2 4 < 1
        60 82 11 77 10 65 9 30 6
        70 120 16 132 16 97 13 69 13
        80 170 22 185 23 174 23 115 21
        90 176 23 248 31 263 35 189 35
        100 31 4 68 8 72 10 62 12
    Zubrod
        0 12 2 16 2 35 5 36 7
        1 36 5 29 4 21 3 26 5
        2 31 4 9 1 4 < 1 2 < 1
        3 16 2 5 1 4 < 1 4 < 1
        4 5 < 1 0 0 1 < 1 0 0
Prior surgery
    Biopsy 223 29 178 22 124 16 94 18
    Partial resection 399 53 436 54 426 56 290 54
    Total resection 114 15 167 21 190 25 140 26
    Other 15 2 26 2 9 1 10 2
    Unknown 5 < 1 8 1 8 1 3 < 1
Neurologic impairment
    None/minor 290 38 421 52 470 62 375 70
    Moderate 351 46 318 40 257 34 151 28
    Severe 107 14 61 8 29 4 9 2
    Unknown/missing 8 1 5 1 1 0 2 0
Mental status
    Normal function 395 52 495 61 486 64 348 65
    Minor mental confusion 294 39 248 31 199 26 125 23
    Gross confusion 41 5 26 3 21 3 7 1
    Rousable with difficulty 4 1 2 < 1 0 0 0 0
    Unknown/missing 22 3 34 4 51 7 57 11
RPA stage
    III 83 11 129 16 119 16 113 21
    IV 246 32 317 39 366 48 271 50
    V 298 39 274 34 215 28 124 23
    VI 127 17 82 10 53 7 28 5
    Unknown 2 < 1 3 < 1 4 < 1 1 < 1

Abbreviation: RPA, recursive partitioning analysis.

*

Karnofsky was collected on studies 9806, 9803, 9710, 9602, 9513, 9417, 9411, 9305, 9006, 8409, 8302, and 7918; Zubrod was collected on studies 0023, 0021, and 0013; both Karnofsky and Zubrod were collected for study 7401 (for that study, Karnofsky performance score is reported where available).