Table 2.
Characteristic | Interval From Surgery to Start of Radiation |
|||||||
---|---|---|---|---|---|---|---|---|
≤ 2 Weeks (n = 756) |
> 2 to 3 Weeks(n = 805) |
> 3 to 4 Weeks (n = 757) |
> 4 Weeks (n = 537) |
|||||
No. | % | No. | % | No. | % | No. | % | |
Days from surgery to start of radiation | ||||||||
Median | 12 | 19 | 26 | 33 | ||||
Range | 1-14 | 15-21 | 22-28 | 29-73 | ||||
Age, years | ||||||||
Median | 57 | 56 | 57 | 55 | ||||
Range | 14-83 | 19-83 | 18-86 | 17-82 | ||||
Dose, Gy | ||||||||
No. of patients with dose | 494 | 676 | 672 | 424 | ||||
Median | 60 | 60 | 60 | 60 | ||||
Range | 1.7-82.87 | 6-85.68 | 2-86 | 2-84.32 | ||||
Performance score* | ||||||||
Karnofsky | ||||||||
20-50 | 77 | 11 | 36 | 4 | 21 | 2 | 4 | < 1 |
60 | 82 | 11 | 77 | 10 | 65 | 9 | 30 | 6 |
70 | 120 | 16 | 132 | 16 | 97 | 13 | 69 | 13 |
80 | 170 | 22 | 185 | 23 | 174 | 23 | 115 | 21 |
90 | 176 | 23 | 248 | 31 | 263 | 35 | 189 | 35 |
100 | 31 | 4 | 68 | 8 | 72 | 10 | 62 | 12 |
Zubrod | ||||||||
0 | 12 | 2 | 16 | 2 | 35 | 5 | 36 | 7 |
1 | 36 | 5 | 29 | 4 | 21 | 3 | 26 | 5 |
2 | 31 | 4 | 9 | 1 | 4 | < 1 | 2 | < 1 |
3 | 16 | 2 | 5 | 1 | 4 | < 1 | 4 | < 1 |
4 | 5 | < 1 | 0 | 0 | 1 | < 1 | 0 | 0 |
Prior surgery | ||||||||
Biopsy | 223 | 29 | 178 | 22 | 124 | 16 | 94 | 18 |
Partial resection | 399 | 53 | 436 | 54 | 426 | 56 | 290 | 54 |
Total resection | 114 | 15 | 167 | 21 | 190 | 25 | 140 | 26 |
Other | 15 | 2 | 26 | 2 | 9 | 1 | 10 | 2 |
Unknown | 5 | < 1 | 8 | 1 | 8 | 1 | 3 | < 1 |
Neurologic impairment | ||||||||
None/minor | 290 | 38 | 421 | 52 | 470 | 62 | 375 | 70 |
Moderate | 351 | 46 | 318 | 40 | 257 | 34 | 151 | 28 |
Severe | 107 | 14 | 61 | 8 | 29 | 4 | 9 | 2 |
Unknown/missing | 8 | 1 | 5 | 1 | 1 | 0 | 2 | 0 |
Mental status | ||||||||
Normal function | 395 | 52 | 495 | 61 | 486 | 64 | 348 | 65 |
Minor mental confusion | 294 | 39 | 248 | 31 | 199 | 26 | 125 | 23 |
Gross confusion | 41 | 5 | 26 | 3 | 21 | 3 | 7 | 1 |
Rousable with difficulty | 4 | 1 | 2 | < 1 | 0 | 0 | 0 | 0 |
Unknown/missing | 22 | 3 | 34 | 4 | 51 | 7 | 57 | 11 |
RPA stage | ||||||||
III | 83 | 11 | 129 | 16 | 119 | 16 | 113 | 21 |
IV | 246 | 32 | 317 | 39 | 366 | 48 | 271 | 50 |
V | 298 | 39 | 274 | 34 | 215 | 28 | 124 | 23 |
VI | 127 | 17 | 82 | 10 | 53 | 7 | 28 | 5 |
Unknown | 2 | < 1 | 3 | < 1 | 4 | < 1 | 1 | < 1 |
Abbreviation: RPA, recursive partitioning analysis.
Karnofsky was collected on studies 9806, 9803, 9710, 9602, 9513, 9417, 9411, 9305, 9006, 8409, 8302, and 7918; Zubrod was collected on studies 0023, 0021, and 0013; both Karnofsky and Zubrod were collected for study 7401 (for that study, Karnofsky performance score is reported where available).