Table 2.
Mean Baseline Scores for the European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 by Treatment Group and Normative Reference Values
| HRQOL Score | Reference Data Normative (n = 1,956) | Reference Data ED-SCLC [19] (n = 271) | Control Arm (n = 131) | PCI Arm (n = 137) |
|---|---|---|---|---|
| Global health status/QOL | 75.3 | 56 | 66 | 67 |
| Functioning | ||||
| Physical | 89.9 | 57 | 66 | 68 |
| Role | 83.3 | 59 | 64 | 67 |
| Emotional | 82.8 | 66 | 80 | 79 |
| Cognitive | 86.5 | 77 | 88 | 90 |
| Social | 85.8 | 68 | 76 | 73 |
| Fatigue | 28.8 | 49 | 35 | 35 |
| Nausea/vomiting | 4 | 12 | 9 | 9 |
| Pain | 20.4 | 36 | 13 | 12 |
| Dyspnea | 14.3 | 49 | 28 | 31 |
| Insomnia | 20.4 | 43 | 24 | 23 |
| Appetite loss | 7.4 | 39 | 17 | 13 |
| Constipation | 10.7 | 28 | 14 | 15 |
| Diarhea | 9.4 | 8 | 7 | 6 |
Abbreviations: HRQOL, health-related quality of life; ED-SCLC, extensive-disease small-cell lung cancer; PCI, prophylactic cranial irradiation; QOL, quality of life.