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. 2008 Nov 10;26(35):5735–5741. doi: 10.1200/JCO.2008.17.1314

Table 3.

Correlation of IL-7 Levels With Lymphocyte Counts Over Time

Level Baseline Day 0 Day +7 Day +14 1 Month 2 Months 3 Months 6 Months 9 Months 12 Months
IL-7, pg/mL
    Median 12.1 37.0 13.5 12.0 9.4 6.5 7.6 9.8 9.0 15.0
    Range 0-46.9 13.3-79.2 3.0-73.0 1.3-74.7 1.3-34.9 1.5-70.0 0.2-68.0 0-43.5 0-71.2 3.2-33.7
ALC, cells/μL
    Median 871 3 76 493 1,138 1,028 1,014 1,298 1,600 1,220
    Range 95-43,817 0-322 6-525 9-2,904 149-3,172 145-5,564 110-3,606 147-4,140 207-3,909 229-5,494
    R −0.49 −0.28 −0.83 −0.35 −0.25 −0.22 −0.08 −0.24 −0.40 −0.22
    P .008 .14 < .0001 .06 .18 .27 .66 .30 .06 .36
CD3, cells/μL
    Median 629 3 60 307 773 777 745 1003 1339 985
    Range 5-2,858 0-69 5-464 6-1,428 128-2,927 112-5,369 97-3,516 95-3,908 172-3,729 200-5,257
    R −0.52 −0.28 −0.82 −0.36 −0.39 −0.22 −0.14 −0.25 −0.38 −0.33
    P .005 .14 < .0001 .05 .04 .28 .47 .29 .07 .15
CD4, cells/μL
    Median 294 3 45 206 405 310 352 439 494 440
    Range 5-1,652 0-65 5-385 5-810 75-1,145 78-901 40-1,493 35-1,457 70-1,176 33-1,032
    R −0.58 −0.22 −0.86 −0.33 −0.36 −0.19 −0.08 −0.34 −0.20 −0.25
    P .001 .24 < .0001 .07 .05 .36 .66 .14 .34 .29
CD8, cells/μL
    Median 269 0 16 95 326 364 356 557 660 397
    Range 1-1,763 0-22 0-88 1-963 27-2,123 31-4,484 57-2,990 57-2,447 98-2,932 165-4,258
    R −0.54 −0.35 −0.65 −0.48 −0.32 −0.22 −0.16 −0.22 −0.46 −0.22
    P .003 .06 .0002 .006 .09 .27 .39 .36 .02 .34

NOTE. Correlation coefficients and P values shown are for comparison with interleukin-7 (IL-7) levels at specified time points.

Abbreviation: ALC, absolute lymphocyte count.