Table A1.
N9741 Treatment Arms
| Treatment | Specific Regimen | Accrual Period | No. of Patients |
|---|---|---|---|
| IFL | Iri + FU/LV + bolus FU/LV | December 1998-April 2002 | 429 |
| FOLFOX | Oxali + bolus FU/LV | May 1999-July 2002 | 696 |
| IROX | Oxali day 1 + Iri | May 1999-March 2002 | 383 |
| Iri/FU | Iri day 1 + bolus FU/LV days 2-5 | November 1998-March 2000 | 61 |
| Iri/FU | Iri + infusional FU/LV weekly | December 1998-April 1999 | 14 |
| Oxali/FU/LV | Oxali day 1 + bolus FU/LV days 1-5 | May 1999-March 2000 | 47 |
| Mayo FU/LV | Iri day 1 + bolus LV + infusional FU days 2-5 | November 1998-March 2000 | 61 |
Abbreviations: IFL, irinotecan plus bolus fluorouracil and leucovorin; Iri, irinotecan; FU, fluorouracil; LV, leucovorin; FOLFOX, oxaliplatin, fluorouracil, and leucovorin; IROX, irinotecan and oxaliplatin; Oxali, oxaliplatin.