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. 2008 Dec 10;26(35):5789–5796. doi: 10.1200/JCO.2008.17.8053

Table 4.

Recommendations for BRCA1 Carriers

Recommendations % of Physicians (N = 611)
Surveillance recommendations for 35-year-old woman with BRCA1 mutation who desires no prophylactic surgery. Recommend … *
    Monthly breast self-examination 95.6
    Clinical breast examination every 6-12 months 74.3
    Mammogram every 6-12 months 95.3
    Pelvic examination every 6-12 months 95.9
    Pelvic ultrasound every 6-12 months 84.6
    CA-125 testing every 6-12 months 74.0
Recommend surveillance breast MRI …
    No 34.7
    Every 6 months 5.7
    Yearly 51.7
    Missing 7.9
38-year-old woman with BRCA1 mutation who has completed childbearing
    Recommend bilateral prophylactic mastectomy 61.4
    Recommend bilateral salpingo-oophorectomy 84.9
38-year-old woman with BRCA1 mutation who has completed childbearing and underwent bilateral prophylactic oophorectomy with hysterectomy
    Recommend estrogen 6.6
    Recommend tamoxifen 71.2
    Recommend raloxifene 33.7

Abbreviation: MRI, magnetic resonance imaging.

*

Time intervals for testing were categorized based on recommendations in published articles and American Society of Clinical Oncology recommendations.