Table 3.
Grade 3, 4, and 5 Toxicity Results
| Toxicity | % of Patients
|
|
|---|---|---|
| CVD Arm (n = 199) | BCT Arm (n = 189) | |
| Leukopenia | 28 | 78 |
| Granulocytopenia | 50 | 46 |
| Thrombocytopenia | 13 | 57 |
| Anemia | 9 | 24 |
| Infection | 5 | 10 |
| Nausea | 11 | 26 |
| Vomiting | 10 | 20 |
| Liver | 4 | 15 |
| Hypotension | 3 | 15 |
| Metabolic | 3 | 22 |
| Fatigue | 4 | 13 |
| Worst degree | ||
| Grade 3 | 34 | 29 |
| Grade 4 | 37 | 64 |
| Grade 5* | 2 | 1 |
| Total | 73 | 95 |
Abbreviations: CVD, cisplatin, vinblastine, and dacarbazine; BCT, biochemotherapy.
*
Three toxic deaths occurred on the CVD arm, and two toxic deaths occurred on the BCT arm.