Table 2.
Multivariate Analysis: Lewis Antigen Negative v CA 19-9 ≤ 180 v CA 19-9 > 180
| Adjustment Variable | Adjusted HR | 95% CI | P* |
|---|---|---|---|
| Gemcitabine v FU | 1.23 | 0.97 to 1.54 | .08 |
| CA 19-9 | |||
| < 180 | — | — | — |
| ≥ 180 | 3.58 | 2.40 to 5.34 | < .0001 |
| Lewis antigen negative | 1.12 | 0.87 to 1.44 | .37 |
| Nodal involvement | |||
| No v yes | 1.46 | 1.13 to 1.89 | .004 |
| Tumor diameter, cm | |||
| < 3 v ≥ 3 | 1.07 | 0.83 to 1.37 | .60 |
| Surgical margin status | |||
| Negative | — | — | — |
| Positive | 1.24 | 0.94 to 1.63 | .13 |
| Unknown | 1.96 | 0.71 to 1.30 | .78 |
Abbreviations: HR, hazards ratio; FU, fluorouracil.
*
P from χ2 test using the Cox proportional hazards model.