Table 5.
Unadjusted Median Time in Days to Symptom Response by Levels of Covariates
| Symptom | Onset Time
|
Chemotherapy Protocol
|
Comorbid Conditions
|
Nonmetastatic Disease
|
Metastatic Disease
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| First Contact | Second or Later Contact | Combination | Single Agent | 0-1 | 2+ | NASM | ATSM | NASM | ATSM | |
| Fatigue | 49.00 | 27.00 | 51.00 | 35.00 | 26.00 | 50.00 | 35.00 | 28.00 | > 57.00 | 55.00 |
| Cough | 21.00 | 14.00 | 18.00 | 14.00 | 18.00 | 14.00 | 14.00 | 10.50 | > 49.00 | 9.00 |
| Anxiety | 21.00 | 14.00 | 14.00 | 21.00 | 14.00 | 21.00 | 22.00 | 21.00 | 22.50 | 14.00 |
| Weakness | 27.00 | 17.00 | 27.00 | 20.00 | 14.00 | 29.00 | 21.50 | 20.00 | 55.00 | 24.00 |
| Appetite | 17.00 | 23.00 | 25.00 | 14.00 | 21.00 | 14.50 | 23.00 | 7.50 | 28.00 | 7.00 |
| Pain | 43.00 | 21.00 | 34.00 | 31.00 | 21.00 | 43.00 | 34.00 | 24.00 | 35.00 | 34.00 |
| Dyspnea | 48.00 | 14.00 | 24.00 | 22.00 | 14.00 | 38.00 | 23.50 | 15.00 | > 49.00 | 11.50 |
| Depression | 24.00 | 14.00 | 20.00 | 19.00 | 14.00 | 24.00 | 47.00 | 14.00 | 24.00 | 14.00 |
| Constipation | 15.00 | 14.00 | 15.00 | 7.50 | 13.00 | 15.00 | 11.00 | 8.50 | 51.00 | 15.00 |
| Vomiting | 9.50 | 7.00 | 11.00 | 8.00 | 9.00 | 7.00 | 8.50 | 8.00 | 10.50 | 14.00 |
| Diarrhea | 7.00 | 8.00 | 7.00 | 7.00 | 8.00 | 7.00 | 7.00 | 7.00 | > 53.00 | 7.00 |
| Dry mouth | 14.00 | 8.00 | 19.00 | 7.00 | 7.00 | 16.00 | 11.50 | 14.00 | 7.00 | 29.00 |
| Sleep disturbance | 22.00 | 28.00 | 22.00 | 24.00 | 22.00 | 28.00 | 31.00 | 21.00 | 18.00 | 14.00 |
| Peripheral neuropathy | 41.00 | 17.00 | 48.00 | 28.00 | 21.00 | 35.50 | 36.00 | 14.50 | > 55.00 | 35.00 |
| Difficulty remembering | 51.00 | 25.00 | 25.00 | 53.00 | 19.00 | 51.00 | 15.00 | > 56.00 | 53.00 | 11.00 |
Abbreviations: NASM, Nurse-Administered Symptom Management; ATSM, Automated Telephone Symptom Management.