Figure 4. Galectin-3-deficient mice exhibit reduced contact hypersensitivity but possess normal antigen-processing capabilities.

(a) Mice were treated on the abdomen with oxazalone and challenged 5 days later on one ear with the hapten and on the contralateral ear with solvent. Ear swelling was determined by measurements with a micrometer. Each experiment was performed with 4 or 5 mice per genotype, and data are means ± SE of two combined experiments. *P<0.05. (b) Uptake and processing of poorly fluorescent DQ-OVA in immature BMiDCs followed by flow-cytometric measurements of fluorescence at the indicated times. Data are representative of two experiments.