TABLE 2.
RELATIVE ABUNDANCE OF MICRORNAS IN THE EMBRYONIC LUNG: THE 20 MOST ABUNDANT MICRORNA FAMILIES IN E17.5 LUNG
| Family Name | Family Members in Mouse | E17.5 Clones | Relative Abundance (%) |
|---|---|---|---|
| let-7 | let-7a/b/c/d/e/f/g/i/miR-98 | 237 | 12.2 |
| miR-15 | miR-15a/15b/16 | 134 | 6.9 |
| miR-17 | miR-17-5p/106a/106b/18/20a/20b/93 | 96 | 4.9 |
| miR-125 | miR-125a/125b | 86 | 4.4 |
| miR-21 | miR-21 | 69 | 3.6 |
| miR-126-3p | miR-126-3p | 63 | 3.2 |
| miR-130 | miR-130a/130b/301a/301b | 61 | 3.1 |
| miR-8 | miR-200a/200b/200c/141/429 | 59 | 3.0 |
| miR-351 | miR-351 | 58 | 3.0 |
| miR-30 | miR-30a/30b/30c/30d/30e | 55 | 2.8 |
| miR-199 | miR-199a/199b | 53 | 2.7 |
| miR-449 | miR-449 | 51 | 2.6 |
| miR-126-5p | miR-126-5p | 48 | 2.5 |
| miR-322 | miR-322 | 40 | 2.1 |
| miR-199a* | miR-199a* | 39 | 2.0 |
| miR-142-3p | miR-142-3p | 36 | 1.9 |
| miR-27 | miR-27a/27b | 34 | 1.8 |
| miR-25 | miR-25/92 | 31 | 1.6 |
| miR-99 | miR-99a/99b/100 | 30 | 1.5 |
| miR-136 | miR-136 | 28 | 1.4 |
A total of 1,668 and 1,941 clones were obtained from E11.5 and E17.5, respectively' 69.1% of E11.5 clones and 89.2% of E17.5 clones are known microRNAs (miRNAs). The definition of miRNA families was derived from http://microrna.sanger.ac.uk.