a) Delivery of payload to cell through monolayer-membrane interactions. b) Structure of particles and guest compounds: Bodipy, TAF, and LAP, the number of encapsulated guests per particle, and logP of the guests. c) Release of Bodipy from AuNPZwit-Bodipy in DCM-aqueous solution two-phase systems (λex = 499 nm, λem = 517 nm) d) PL intensity AuNPZwit-Bodipy in cell culture medium and 100 % serum, indicating little or no release relative to AuNPZwit-Bodipy in PBS after NaCN-induced release of guest molecules ((λex = 499 nm, λem = 510 nm).