TABLE 1.
SUMMARY OF AGENTS THAT MODULATE ASM CELL MIGRATION
| PROMIGRATORY AGENTS |
| Growth Factors and Cytokines |
| BFGF (80) |
| CC Chemokine ligand 19 (CCL19) (81) |
| IL-1β (31) |
| IL-8 (82) |
| Leukotriene E4 (34) |
| PDGF (31, 64, 83) |
| TGFβ1 (31) |
| Extracellular Matrix |
| Collagens I, III, V (34) |
| Fibronectin (34) |
| Laminin (34) |
| Integrins α5, αV (34) |
| Other Promigratory Agents |
| Cyclodextrin (62) |
| Lysophosphatidic acid (39) |
| Thrombin (21) |
| Urokinase plasminogen activator (29, 71) |
| ANTIMIGRATORY AGENTS |
| β-adrenergic Agonists and the PKA pathway |
| Dibutyryl cAMP (39) |
| Formeterol (29) |
| Forskolin (80) |
| Cilomolast (80) |
| Salmeterol (80) |
| Theophylline (39) |
| Immunomodulating Drugs |
| Fluticasone (80) |
| Pyrimidine synthesis inhibitor, FK778 (84) |
| Sirolimus (84) |
| Protease Inhibitors |
| 4-(2-Aminoethyl) benzenesulfonylfluoride HCl (AEBSF) (21) |
| Ilomastat (21) |
| Prinomastat (20) |
| TIMPs 1-4 (21) |
| Protein Kinase and Phosphatase Inhibitors |
| LY294002 (34, 65) |
| PP1 (16) |
| PD98059 (31) |
| SB203580 (31, 34) |
| U-0126 (29, 65) |
| Vanadate (62) |
| Y27632 (34, 39) |
| Other Antimigratory Agents |
| Pertussis toxin (29) |
| Prostaglandin E2 (34) |
| Retinoic acid (65) |
| SB649146 (SP-1 inverse agonist) (83) |