TABLE 1.

COMPARSION OF BRITISH MEDICAL RESEARCH COUNCIL AND NOCTURNAL OXYGEN THERAPY TRIAL LONG-TERM OXYGEN TREATMENT TRIALS

	MRC	NOTT
Number	87	203
Study design	Prospective, controlled	Prospective, controlled
Protocol	No O2 vs. nocturnal use	Nocturnal vs. continuous use
FEV1	0.58–0.76 L	29% predicted
Female, %	24	20–23
PaO2, mm Hg	49–51	51
PaCO2, mm Hg	55–60	43
MPAP, mm Hg	32–35	30
Hours of O2 use/d	0 vs. 15	12 ± 2.5 vs. 17.7 ± 4.8
Smoking status	25–52%	—

Definition of abbreviations: MPAP = mean pulmonary artery pressure; MRC = Medical Research Council; NOTT = Nocturnal Oxygen Therapy Trial.

Modified by permission from Reference 55.