. Author manuscript; available in PMC: 2009 Feb 19.

Published in final edited form as: Neuropsychopharmacology. 2007 Sep 19;33(8):1992–2006. doi: 10.1038/sj.npp.1301581

Table 3.

Regions showing a main effect (i.e. independent of depletion condition) of emotional content on regional BOLD response to target stimuli

Region	Laterality	Stereotaxic coordinates			Cluster size	Z value
Emotional>neutral targets		X	Y	Z
Posterior cingulate C	M	0	−51	25	1483^†	5.00 ^*^b
Ventromedial frontal polar C	M	−4	58	−1	270^†	4.98^*^b
Mid-cingulate G	M	2	− 16	21	85	4.17^a
Pregenual anterior cingulate C	M	−4	45	16	123	3.78^b
Superior temporal G	R	48	−63	27	47	3.62^b
Neutral>emotional targets
Dorsal anterior cingulate C	R	6	12	44	521^†	5.41^*^a
Dorsolateral PFC	L	−42	3	26	1318^†	4.99^*^a
Lateral orbitofrontal C	R	42	27	−5	372^†	4.73^a
Inferior temporal G	L	−44	−59	−14	131	4.54^a
Dorsolateral prefrontal C	R	50	36	20	1343^†	4.52^a
Fusiform G	R	38	−51	−19	56	4.30^a 37
Medial cerebellum	L	−8	−79	−28	116	4.06^a
Superior parietal C	R	40	−41	41	106	4.06^a
Occipital C	R	44	−69	−12	79	3.86^a
Superior parietal C	L	−22	−66	44	206^†	3.84^a
Dorsolateral prefrontal C	R	38	3	53	21	3.78^a
Parietal C	R	28	−58	47	99	3.67^a
Occipital C	R	28	−70	29	41	3.60^a
Happy>sad targets
Occipital C	R	8	−80	−4	23	3.92^b
Ventrolateral prefrontal C	R	51	19	25	42	3.92^a
Medial cerebellum	L	−12	−79	−28	20	3.82^a
Ventrolateral prefrontal C	L	−44	35	−2	75	3.61^a
Medial cerebellum	R	10	−77	−16	27	3.45^a

Coordinates correspond to the stereotaxic array ofTalairach and Tournoux (1988) and denote the distance in mm from the anterior commissure, with positive×= right of midline, positive y = anterior to the anterior commissure, and positive z = dorsal to a plane containing both the anterior and the posterior commissures.

Abbreviations: BA 10P – Brodmann Area 10 polar (see Ongur et al. 2003); C – cortex; G – gyrus; L – left; M – midline; R – right

peak voxel significant at p<0.05 (FWE corrected for multiple comparisons)

^†

cluster significant at p<0.05 (corrected in terms of spatial extent)

parameter estimates positive relative to rest

parameter estimates negative relative to rest. Italic font denotes that the maximum was contained within an a priori specified region of interest.