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. 2009 Feb 2;10:43. doi: 10.1186/1471-2105-10-43

Table 2.

Validation using different combinations among samples

Validation sample set Sample Control P FP FDR
I SP/RP (UL) SP/RP (IS) 22 1 0.045

II SA/SB (UL) SA/SB (IS) 8 2 -

SB/SC (UL) SB/SC (IS) 0 1 -

SC/SA (UL) SC/SA (IS) 1 0 -

Average 3.0 1.0 0.33

III SP/RP (UL) SA/SB (UL) 22 8 -

SB/SC (UL) 22 0 -

SC/SA (UL) 22 1 -

Average 22 3.0 0.14

IV SP/RP (IS) SA/SB (IS) 1 2 -

SB/SC (IS) 1 1 -

SC/SA (IS) 1 0 -

Average 1.0 1.0 1.0

V SP/RP (UL) Inj.1 vs Inj.2 (UL) of SP, SA, SB, and SC 22 0 0.00

Sample set I represents the target of validation. The parameters used for FDR calculation were: 2-fold change, 4 MPSP, and t-test (p < 0.05). P, positives. FP, false positives. '-', not calculated. See text for more details.