Table 2.
5-HT1A C(-1019)G allele distribution in control and depressed subjects.
| Subject | N | C/C | C/G | G/G | Allele C | Allele G |
|---|---|---|---|---|---|---|
| Female | ||||||
| Control | 13 | 4 | 7 | 2 | 15 | 11 |
| Depressed | 13 | 5 | 6 | 2 | 16 | 10 |
|
| ||||||
| Male | ||||||
| Control | 12 | 6 | 4 | 2 | 16 | 8 |
| Depressed | 12 | 3 | 6 | 3 | 12 | 12 |
Genotype frequencies were analyzed using a two-tailed Chi-squared test and allele frequencies were analyzed using a two-tailed Fisher's exact test.
For genotype frequency of control versus depressed subjects: female subject group Chi-squared=0.1880; df=2; P=0.9103; male subject group Chi-squared=0.600, df=2; P=0.4493; all Chi-squared=0.3768; df=2; P=0.8283. For allele frequency of control versus depressed subjects: female, P=1.0; male, P=.3801; all, P=0.6845