Table 1.TRPV1.
Compound | Structure | Origin | Action | Conc. Range |
---|---|---|---|---|
Capsaicin | Capsicum genus | Activates (17) | 10-8-10-6M | |
Piperine | Piper nigrum/ longum | Activates (69) | 10-5-10-4 M | |
Eugenol | Clove oil | Activates (137) | 10-3-10-2 M | |
Resiniferatoxin | Euphorbia resinifera | Activates (17) | 10-10-10-8 M | |
Gingerol | Zingiber officinale | Activates (43) | 10-4 M | |
Zingerone | Zingiber officinale | Activates (59) | 10-2 M | |
Evodiamine | Evodia rutaecarpa | Activates (89) | 10-6-10-5M | |
Cannabidiol | Cannabis sativa | Activates (10) | 10-6-10-5 M | |
Polygodial | Polygonum hydropiper | Activates (2) | 10-6-10-5 M | |
Isovelleral | Lactarius vellereus | Activates (94, 114) | ||
Camphor | Cinnamomum camphora | Activates (134) | 10-3-10-2 M | |
Vanillotoxin 1, 2 and 3 | Psalmopoeus cambridgei | Activates (99) | 10-8-10-4 M | |
Cnidarian envenomations | jellyfish | Activates (23) | ||
Thapsigargin | Thapsia garganica | Inhibits (120) | 10-6-10-5 M | |
Yohimbine | Pausinystalia yohimbe | Inhibits (28) | 10-5-10-4 M | |
AG489 toxin | Agelenopsis aperta | Inhibits (48) | 10-7 M | |
AG505 toxin | Agelenopsis aperta | Inhibits (48) | 10-7M |